What is the best allergy medicine for indoor and outdoor allergies

The symptoms of allergic rhinitis may at first feel love those of a freezing. But unlike a freezing that may incubate before causing discomfort, symptoms of allergies generally appear almost as soon as a person encounters an allergen, such as pollen or mold.

Symptoms include itchy eyes, ears, nose or throat, sneezing, irritability, nasal congestion and hoarseness. People may also experience cough, postnasal drip, sinus pressure or headaches, decreased sense of smell, snoring, sleep apnea, fatigue and asthma, Josephson said. [Oral Allergy Syndrome: 6 Ways to Avoid an Itchy, Tingling Mouth]

Many of these symptoms are the immune system’s overreaction as it attempts to protect the vital and sensitive respiratory system from exterior invaders.

The antibodies produced by the body hold the foreign invaders out, but also cause the symptoms characteristic of allergic responses.

People can develop hay fever at any age, but most people are diagnosed with the disorder in childhood or early adulthood, according to the Mayo Clinic. Symptoms typically become less severe as people age.

Often, children may first experience food allergies and eczema, or itchy skin, before developing hay fever, Josephson said. «This then worsens over the years, and patients then develop allergies to indoor allergens love dust and animals, or seasonal rhinitis, love ragweed, grass pollen, molds and tree pollen.»

Hay fever can also lead to other medical conditions.

People who are allergic to weeds are more likely to get other allergies and develop asthma as they age, Josephson said. But those who get immunotherapy, such as allergy shots that assist people’s bodies get used to allergens, are less likely to develop asthma, he said.


Tests & diagnosis

A physician will consider patient history and act out a thorough physical examination if a person reports having hay-fever-like symptoms.

If necessary, the physician will do an allergy test. According to the Mayo Clinic, people can get a skin-prick test, in which doctors prick the skin on a person’s arm or upper back with diverse substances to see if any cause an allergic reaction, such as a raised bump called a hive. [7 Strange Signs You’re Having an Allergic Reaction]

Blood tests for allergies are also available. This test rates the immune system’s response to a specific allergen by measuring the quantity of allergy-causing antibodies in the bloodstream, according to the Mayo Clinic.


Hay fever treatments

Dr.

Sarita Patil, an allergist with Massachusetts General Hospital’s Allergy Associates in Boston, talked to Live Science about strategies for outdoor lovers with seasonal allergies.

Patil suggested figuring out exactly what type of pollen you’re allergic to, and then avoiding planning outdoor activities during peak pollinating times in the months when those plants are in bloom. Numerous grasses, for example, typically pollinate in tardy spring and early summer and release most of their spores in the afternoon and early evening.

Her other strategies: Be capable to identify the pollen perpetrator by sight; monitor pollen counts before scheduling outdoor time; go exterior at a time of day when the plants that make you go achoo are not pollinating; and wear protective gear love sunglasses, among other tips.

[7 Strategies for Outdoor Lovers with Seasonal Allergies]

Allergy sufferers may also select to combat symptoms with medication designed to shut below or trick the immune sensitivity in the body. Whether over-the-counter or prescription, most allergy pills work by releasing chemicals into the body that bind naturally to histamine — the protein that reacts to the allergen and causes an immune response — negating the protein’s effect.

Other allergy remedies attack the symptoms at the source. Nasal sprays contain athletic ingredients that decongest by soothing irritated blood vessels in the nose, while eye drops both moisturize and reduce inflammation.

Doctors may also prescribe allergy shots, Josephson said.

For kids, allergy medications are tricky. A 2017 nationally representative poll of parents with kids between ages 6 and 12 found that 21% of parents said they had trouble figuring out the correct dose of allergy meds for their child; 15% of parents gave a kid an adult form of the allergy medicine, and 33% of these parents also gave their kid the adult dose of that medicine.

Doctors may also recommend allergy shots, a neti pot that can rinse the sinuses, or a Grossan Hydropulse — an irrigating system that cleans the nose of pollens, infection and environmental irritants, Josephson said.

Alternative and holistic options, along with acupuncture, may also assist people with hay fever, Josephson said.

People can also avoid pollen by keeping their windows closed in the spring, and by using air purifiers and air conditioners at home.

Probiotics may also be helpful in stopping those itchy eyes and runny noses. A 2015 review published in the journal International Forum of Allergy and Rhinology found that people who suffer from hay fever may benefit from using probiotics, or «good bacteria,» thought to promote a healthy gut. Although the jury is still out on whether probiotics are an effective treatment for seasonal allergies, the researchers noted that these gut bacteria could hold the body’s immune system from flaring up in response to allergens — something that could reduce allergy symptoms.

[5 Myths About Probiotics]

Additional resources:

This article was updated on April 30, 2019, by Live Science Contributor Rachel Ross.

SAN DIEGO—(BUSINESS WIRE)—Innovus Pharmaceuticals, Inc. («Innovus Pharma» or the “Company”) (OTCQB Venture Market: INNV), an emerging commercial-stage pharmaceutical company that delivers safe, innovative and effective over-the-counter medicine and consumer care products to improve men’s and women’s health and respiratory diseases, today announced that its FlutiCare® OTC product for the relief of seasonal allergies is currently ranked #2 behind Flonase® in Amazon®’s Fluticasone Propionate and Allergy Nasal Spray categories.

In addition, FlutiCare® is currently ranked #6 in Amazon’s Best Moisturizing Nasal Sprays category, #11 in the Best Allergy Medicine category and #41 in the Sinus Medicine category. To meet the growing demand on Amazon® for FlutiCare®, Innovus Pharma placed an additional order of 220,000 units with its manufacturer.

FlutiCare® contains the most prescribed nasal steroid athletic pharmaceutical ingredient (“API”) and form for nasal allergy relief over the final 7 years. FlutiCare® is available OTC with the same prescription strength and same delivery method as Flonase®* and ClariSpray®*. The Company currently believes that FlutiCare® is the most affordable fluticasone propionate nasal spray on the market and is now available in a one dose, 30 Day (120 Sprays) treatment and is the only one providing a monthly autoship plan.

“We are extremely excited to announce the current high ranking of our FlutiCare® product in certain Amazon indication categories,” said Dr. Bassam Damaj, President and Chief Executive Officer of Innovus Pharma. “FlutiCare® traces its roots as the most prescribed Rx 24-hour nasal allergy spray API and form in the U.S. over the past 7 years by a factor of over 10 to 1 and the number of units we sell has continued to grow. As sales of the product are increasing significantly, we felt it was necessary to increase our supply of this product to meet our consumers’ growing demand,” he continued.

About FlutiCare®

FlutiCare® is a nasal spray, which provides 50 micrograms of fluticasone propionate (“USP”) per spray, a nasal corticosteroid that provides 24-hour temporary relief of seasonal and perennial nasal allergy symptoms. FlutiCare® can be used to relieve both indoor and outdoor nasal allergy symptoms caused by pollen, dust, animal dander, and other indoor and outdoor allergens. Nasal allergy symptoms include nasal congestion, runny nose, sneezing, itchy nose, etc.

FlutiCare® contains the nasal steroid API that is physician recommended and consumer preferred.

  1. Familiar to patients, comfort of a known & trusted medicine;
  2. Engrained in patients’ allergy management; and
  3. #1 nasal steroid athletic prescribed by physicians;
  4. #1 form used by patients;
  5. Effective and safe.

About Innovus Pharmaceuticals, Inc.

Headquartered in San Diego, Innovus Pharma is an emerging OTC consumer goods and specialty pharmaceutical company engaged in the commercialization, licensing and development of safe and effective non-prescription medicine and consumer care products to improve men’s and women’s health and vitality and respiratory diseases.

Innovus Pharma delivers innovative and uniquely presented and packaged health solutions through its (a) OTC medicines and consumer and health products, which we market directly, (b) commercial partners to primary care physicians, urologists, gynecologists and therapists, and (c) directly to consumers through our on-line channels, retailers and wholesalers. The Company is dedicated to being a leader in developing and marketing new OTC and branded Abbreviated New Drug Application (“ANDA”) products. The Company is actively pursuing opportunities where existing prescription drugs own recently, or are expected to, change from prescription (or Rx) to OTC.

For more information, go to www.innovuspharma.com; www.zestra.com; www.ejectdelay.com; www.myvesele.com; www.urivarx.com; www.sensumplus.com; www.myandroferti.com; www.beyondhumantestosterone.com; www.getbeyondhuman.com; www.trybeyondhuman.com; www.recalmax.com; www.prostagorx.com; www.xyralid.com; www.fluticare.com; www.allervarx.com; and www.apeaz.com.

Innovus Pharma’s Forward-Looking Safe Harbor:

Statements under the Private Securities Litigation Reform Act, as amended: with the exception of the historical information contained in this release, the matters described herein contain forward-looking statements that involve risks and uncertainties that may individually or mutually impact the matters herein described for a variety of reasons that are exterior the control of the Company, including, but not limited to, projected revenues from its FlutiCare® product, estimated market for its products, and statements about achieving its other development, growth, commercialization, financial and staffing objectives.

Readers are cautioned not to put undue reliance on these forward-looking statements as actual results could differ materially from the forward-looking statements contained herein. Readers are urged to read the risk factors set forth in the Company’s most recent filing on Form S-1, annual report on Form 10-K, subsequent quarterly reports filed on Form 10-Q and other filings made with the SEC. Copies of these reports are available from the SEC’s website or without charge from the Company.

*Flonase® is a registered trademark of GSK and ClariSpray® is a registered trademark of Bayer.

Medications

Many allergens that trigger allergic rhinitis are airborne, so you can’t always avoid them. If your symptoms can’t be well-controlled by simply avoiding triggers, your allergist may recommend medications that reduce nasal congestion, sneezing, and an itchy and runny nose. They are available in numerous forms — oral tablets, liquid medication, nasal sprays and eyedrops. Some medications may own side effects, so discuss these treatments with your allergist so they can assist you live the life you want.

Nasal sprays

Nonprescription saline nasal sprays will assist counteract symptoms such as dry nasal passages or thick nasal mucus.

Unlike decongestant nasal sprays, a saline nasal spray can be used as often as it is needed. Sometimes an allergist may recommend washing (douching) the nasal passage. There are numerous OTC delivery systems for saline rinses, including neti pots and saline rinse bottles.

Nasal cromolyn blocks the body’s release of allergy-causing substances. It does not work in every patients. The full dose is four times daily, and improvement of symptoms may take several weeks. Nasal cromolyn can assist prevent allergic nasal reactions if taken prior to an allergen exposure.

Nasal ipratropium bromide spray can assist reduce nasal drainage from allergic rhinitis or some forms of nonallergic rhinitis.

Immunotherapy

Immunotherapy may be recommended for people who don’t reply well to treatment with medications or who experience side effects from medications, who own allergen exposure that is unavoidable or who desire a more permanent solution to their allergies.

Immunotherapy can be extremely effective in controlling allergic symptoms, but it doesn’t assist the symptoms produced by nonallergic rhinitis.

Two types of immunotherapy are available: allergy shots and sublingual (under-the-tongue) tablets.

  1. Allergy shots: A treatment program, which can take three to five years, consists of injections of a diluted allergy extract, istered frequently in increasing doses until a maintenance dose is reached. Then the injection schedule is changed so that the same dose is given with longer intervals between injections.

    Immunotherapy helps the body build resistance to the effects of the allergen, reduces the intensity of symptoms caused by allergen exposure and sometimes can actually make skin test reactions vanish. As resistance develops over several months, symptoms should improve.

  2. Sublingual tablets: This type of immunotherapy was approved by the Food and Drug istration in 2014. Starting several months before allergy season begins, patients dissolve a tablet under the tongue daily. Treatment can continue for as endless as three years. Only a few allergens (certain grass and ragweed pollens and home dust mite) can be treated now with this method, but it is a promising therapy for the future.

Leukatriene pathway inhibitors

Leukotriene pathway inhibitors (montelukast, zafirlukast and zileuton) block the action of leukotriene, a substance in the body that can cause symptoms of allergic rhinitis.

These drugs are also used to treat asthma.

Decongestants

Decongestants assist relieve the stuffiness and pressure caused by swollen nasal tissue.

What is the best allergy medicine for indoor and outdoor allergies

They do not contain antihistamines, so they do not cause antihistaminic side effects. They do not relieve other symptoms of allergic rhinitis. Oral decongestants are available as prescription and nonprescription medications and are often found in combination with antihistamines or other medications. It is not unusual for patients using decongestants to experience insomnia if they take the medication in the afternoon or evening. If this occurs, a dose reduction may be needed. At times, men with prostate enlargement may encounter urinary problems while on decongestants. Patients using medications to manage emotional or behavioral problems should discuss this with their allergist before using decongestants.

Patients with high blood pressure or heart disease should check with their allergist before using. Pregnant patients should also check with their allergist before starting decongestants.

Nonprescription decongestant nasal sprays work within minutes and final for hours, but you should not use them for more than a few days at a time unless instructed by your allergist. Prolonged use can cause rhinitis medicamentosa, or rebound swelling of the nasal tissue. Stopping the use of the decongestant nasal spray will cure that swelling, provided that there is no underlying disorder.

Oral decongestants are found in numerous over-the-counter (OTC) and prescription medications, and may be the treatment of choice for nasal congestion.

They don’t cause rhinitis medicamentosa but need to be avoided by some patients with high blood pressure. If you own high blood pressure or heart problems, check with your allergist before using them.

Antihistamines

Antihistamines are commonly used to treat allergic rhinitis. These medications counter the effects of histamine, the irritating chemical released within your body when an allergic reaction takes put. Although other chemicals are involved, histamine is primarily responsible for causing the symptoms. Antihistamines are found in eyedrops, nasal sprays and, most commonly, oral tablets and syrup.

Antihistamines assist to relieve nasal allergy symptoms such as:

  1. Eye itching, burning, tearing and redness
  2. Sneezing and an itchy, runny nose
  3. Itchy skin, hives and eczema

There are dozens of antihistamines; some are available over the counter, while others require a prescription.

Patients reply to them in a wide variety of ways.

Generally, the newer (second-generation) products work well and produce only minor side effects. Some people discover that an antihistamine becomes less effective as the allergy season worsens or as their allergies change over time. If you discover that an antihistamine is becoming less effective, tell your allergist, who may recommend a diverse type or strength of antihistamine. If you own excessive nasal dryness or thick nasal mucus, consult an allergist before taking antihistamines. Contact your allergist for advice if an antihistamine causes drowsiness or other side effects.

Proper use: Short-acting antihistamines can be taken every four to six hours, while timed-release antihistamines are taken every 12 to 24 hours.

The short-acting antihistamines are often most helpful if taken 30 minutes before an anticipated exposure to an allergen (such as at a picnic during ragweed season). Timed-release antihistamines are better suited to long-term use for those who need daily medications. Proper use of these drugs is just as significant as their selection. The most effective way to use them is before symptoms develop. A dose taken early can eliminate the need for numerous later doses to reduce established symptoms. Numerous times a patient will tell that he or she “took one, and it didn’t work.” If the patient had taken the antihistamine regularly for three to four days to build up blood levels of the medication, it might own been effective.

Side effects: Older (first-generation) antihistamines may cause drowsiness or performance impairment, which can lead to accidents and personal injury.

Even when these medications are taken only at bedtime, they can still cause considerable impairment the following day, even in people who do not feel drowsy. For this reason, it is significant that you do not drive a car or work with dangerous machinery when you take a potentially sedating antihistamine. Some of the newer antihistamines do not cause drowsiness.

A frequent side effect is excessive dryness of the mouth, nose and eyes.

What is the best allergy medicine for indoor and outdoor allergies

Less common side effects include restlessness, nervousness, overexcitability, insomnia, dizziness, headaches, euphoria, fainting, visual disturbances, decreased appetite, nausea, vomiting, abdominal distress, constipation, diarrhea, increased or decreased urination, urinary retention, high or low blood pressure, nightmares (especially in children), sore throat, unusual bleeding or bruising, chest tightness or palpitations. Men with prostate enlargement may encounter urinary problems while on antihistamines. Consult your allergist if these reactions occur.

Important precautions:

  1. Keep these medications out of the reach of children.
  2. While antihistamines own been taken safely by millions of people in the final 50 years, don’t take antihistamines before telling your allergist if you are allergic to, or intolerant of, any medicine; are pregnant or intend to become pregnant while using this medication; are breast-feeding; own glaucoma or an enlarged prostate; or are ill.
  3. Some antihistamines appear to be safe to take during pregnancy, but there own not been enough studies to determine the absolute safety of antihistamines in pregnancy.

    Again, consult your allergist or your obstetrician if you must take antihistamines.

  4. Do not use more than one antihistamine at a time, unless prescribed.
  5. Know how the medication affects you before working with heavy machinery, driving or doing other performance-intensive tasks; some products can slow your reaction time.
  6. Alcohol and tranquilizers increase the sedation side effects of antihistamines.
  7. Follow your allergist’s instructions.
  8. Never take anyone else’s medication.

Intranasal corticosteroids

Intranasal corticosteroids are the single most effective drug class for treating allergic rhinitis.

They can significantly reduce nasal congestion as well as sneezing, itching and a runny nose.

Ask your allergist about whether these medications are appropriate and safe for you. These sprays are designed to avoid the side effects that may happen from steroids that are taken by mouth or injection. Take care not to spray the medication against the middle portion of the nose (the nasal septum). The most common side effects are local irritation and nasal bleeding. Some older preparations own been shown to own some effect on children’s growth; data about some newer steroids don’t indicate an effect on growth.

Eye allergy preparations and eyedrops

Eye allergy preparations may be helpful when the eyes are affected by the same allergens that trigger rhinitis, causing redness, swelling, watery eyes and itching.

OTC eyedrops and oral medications are commonly used for short-term relief of some eye allergy symptoms. They may not relieve every symptoms, though, and prolonged use of some of these drops may actually cause your condition to worsen.

Prescription eyedrops and oral medications also are used to treat eye allergies. Prescription eyedrops provide both short- and long-term targeted relief of eye allergy symptoms, and can be used to manage them.

Check with your allergist or pharmacist if you are unsure about a specific drug or formula.

Hay fever treatments

Dr.

Sarita Patil, an allergist with Massachusetts General Hospital’s Allergy Associates in Boston, talked to Live Science about strategies for outdoor lovers with seasonal allergies.

Patil suggested figuring out exactly what type of pollen you’re allergic to, and then avoiding planning outdoor activities during peak pollinating times in the months when those plants are in bloom. Numerous grasses, for example, typically pollinate in tardy spring and early summer and release most of their spores in the afternoon and early evening.

Her other strategies: Be capable to identify the pollen perpetrator by sight; monitor pollen counts before scheduling outdoor time; go exterior at a time of day when the plants that make you go achoo are not pollinating; and wear protective gear love sunglasses, among other tips.

[7 Strategies for Outdoor Lovers with Seasonal Allergies]

Allergy sufferers may also select to combat symptoms with medication designed to shut below or trick the immune sensitivity in the body. Whether over-the-counter or prescription, most allergy pills work by releasing chemicals into the body that bind naturally to histamine — the protein that reacts to the allergen and causes an immune response — negating the protein’s effect.

Other allergy remedies attack the symptoms at the source.

What is the best allergy medicine for indoor and outdoor allergies

Nasal sprays contain athletic ingredients that decongest by soothing irritated blood vessels in the nose, while eye drops both moisturize and reduce inflammation. Doctors may also prescribe allergy shots, Josephson said.

For kids, allergy medications are tricky. A 2017 nationally representative poll of parents with kids between ages 6 and 12 found that 21% of parents said they had trouble figuring out the correct dose of allergy meds for their child; 15% of parents gave a kid an adult form of the allergy medicine, and 33% of these parents also gave their kid the adult dose of that medicine.

Doctors may also recommend allergy shots, a neti pot that can rinse the sinuses, or a Grossan Hydropulse — an irrigating system that cleans the nose of pollens, infection and environmental irritants, Josephson said.

Alternative and holistic options, along with acupuncture, may also assist people with hay fever, Josephson said.

People can also avoid pollen by keeping their windows closed in the spring, and by using air purifiers and air conditioners at home.

Probiotics may also be helpful in stopping those itchy eyes and runny noses. A 2015 review published in the journal International Forum of Allergy and Rhinology found that people who suffer from hay fever may benefit from using probiotics, or «good bacteria,» thought to promote a healthy gut. Although the jury is still out on whether probiotics are an effective treatment for seasonal allergies, the researchers noted that these gut bacteria could hold the body’s immune system from flaring up in response to allergens — something that could reduce allergy symptoms.

[5 Myths About Probiotics]

Additional resources:

This article was updated on April 30, 2019, by Live Science Contributor Rachel Ross.

SAN DIEGO—(BUSINESS WIRE)—Innovus Pharmaceuticals, Inc. («Innovus Pharma» or the “Company”) (OTCQB Venture Market: INNV), an emerging commercial-stage pharmaceutical company that delivers safe, innovative and effective over-the-counter medicine and consumer care products to improve men’s and women’s health and respiratory diseases, today announced that its FlutiCare® OTC product for the relief of seasonal allergies is currently ranked #2 behind Flonase® in Amazon®’s Fluticasone Propionate and Allergy Nasal Spray categories.

In addition, FlutiCare® is currently ranked #6 in Amazon’s Best Moisturizing Nasal Sprays category, #11 in the Best Allergy Medicine category and #41 in the Sinus Medicine category. To meet the growing demand on Amazon® for FlutiCare®, Innovus Pharma placed an additional order of 220,000 units with its manufacturer.

FlutiCare® contains the most prescribed nasal steroid athletic pharmaceutical ingredient (“API”) and form for nasal allergy relief over the final 7 years. FlutiCare® is available OTC with the same prescription strength and same delivery method as Flonase®* and ClariSpray®*. The Company currently believes that FlutiCare® is the most affordable fluticasone propionate nasal spray on the market and is now available in a one dose, 30 Day (120 Sprays) treatment and is the only one providing a monthly autoship plan.

“We are extremely excited to announce the current high ranking of our FlutiCare® product in certain Amazon indication categories,” said Dr. Bassam Damaj, President and Chief Executive Officer of Innovus Pharma. “FlutiCare® traces its roots as the most prescribed Rx 24-hour nasal allergy spray API and form in the U.S. over the past 7 years by a factor of over 10 to 1 and the number of units we sell has continued to grow. As sales of the product are increasing significantly, we felt it was necessary to increase our supply of this product to meet our consumers’ growing demand,” he continued.

About FlutiCare®

FlutiCare® is a nasal spray, which provides 50 micrograms of fluticasone propionate (“USP”) per spray, a nasal corticosteroid that provides 24-hour temporary relief of seasonal and perennial nasal allergy symptoms.

FlutiCare® can be used to relieve both indoor and outdoor nasal allergy symptoms caused by pollen, dust, animal dander, and other indoor and outdoor allergens. Nasal allergy symptoms include nasal congestion, runny nose, sneezing, itchy nose, etc.

FlutiCare® contains the nasal steroid API that is physician recommended and consumer preferred.

  1. Familiar to patients, comfort of a known & trusted medicine;
  2. Engrained in patients’ allergy management; and
  3. #1 nasal steroid athletic prescribed by physicians;
  4. #1 form used by patients;
  5. Effective and safe.

About Innovus Pharmaceuticals, Inc.

Headquartered in San Diego, Innovus Pharma is an emerging OTC consumer goods and specialty pharmaceutical company engaged in the commercialization, licensing and development of safe and effective non-prescription medicine and consumer care products to improve men’s and women’s health and vitality and respiratory diseases. Innovus Pharma delivers innovative and uniquely presented and packaged health solutions through its (a) OTC medicines and consumer and health products, which we market directly, (b) commercial partners to primary care physicians, urologists, gynecologists and therapists, and (c) directly to consumers through our on-line channels, retailers and wholesalers.

The Company is dedicated to being a leader in developing and marketing new OTC and branded Abbreviated New Drug Application (“ANDA”) products. The Company is actively pursuing opportunities where existing prescription drugs own recently, or are expected to, change from prescription (or Rx) to OTC.

For more information, go to www.innovuspharma.com; www.zestra.com; www.ejectdelay.com; www.myvesele.com; www.urivarx.com; www.sensumplus.com; www.myandroferti.com; www.beyondhumantestosterone.com; www.getbeyondhuman.com; www.trybeyondhuman.com; www.recalmax.com; www.prostagorx.com; www.xyralid.com; www.fluticare.com; www.allervarx.com; and www.apeaz.com.

Innovus Pharma’s Forward-Looking Safe Harbor:

Statements under the Private Securities Litigation Reform Act, as amended: with the exception of the historical information contained in this release, the matters described herein contain forward-looking statements that involve risks and uncertainties that may individually or mutually impact the matters herein described for a variety of reasons that are exterior the control of the Company, including, but not limited to, projected revenues from its FlutiCare® product, estimated market for its products, and statements about achieving its other development, growth, commercialization, financial and staffing objectives.

Readers are cautioned not to put undue reliance on these forward-looking statements as actual results could differ materially from the forward-looking statements contained herein. Readers are urged to read the risk factors set forth in the Company’s most recent filing on Form S-1, annual report on Form 10-K, subsequent quarterly reports filed on Form 10-Q and other filings made with the SEC. Copies of these reports are available from the SEC’s website or without charge from the Company.

*Flonase® is a registered trademark of GSK and ClariSpray® is a registered trademark of Bayer.

Avoidance

The first approach in managing seasonal or perennial forms of hay fever should be to avoid the allergens that trigger symptoms.

Outdoor exposure

  1. Wear glasses or sunglasses when outdoors to minimize the quantity of pollen getting into your eyes.
  2. Don’t hang clothing outdoors to dry; pollen may cling to towels and sheets.
  3. Wear a pollen mask (such as a NIOSH-rated 95 filter mask) when mowing the lawn, raking leaves or gardening, and take appropriate medication beforehand.
  4. Avoid using window fans that can draw pollens and molds into the house.
  5. Stay indoors as much as possible when pollen counts are at their peak, generally during the midmorning and early evening (this may vary according to plant pollen), and when wind is blowing pollens around.
  6. Try not to rub your eyes; doing so will irritate them and could make your symptoms worse.

Indoor exposure

  1. Reduce exposure to dust mites, especially in the bedroom.

    Use “mite-proof” covers for pillows, comforters and duvets, and mattresses and box springs. Wash your bedding frequently, using boiling water (at least 130 degrees Fahrenheit).

  2. To limit exposure to mold, hold the humidity in your home low (between 30 and 50 percent) and clean your bathrooms, kitchen and basement regularly. Use a dehumidifier, especially in the basement and in other damp, humid places, and empty and clean it often.

    If mold is visible, clean it with mild detergent and a 5 percent bleach solution as directed by an allergist.

  3. Keep windows closed, and use air conditioning in your car and home. Make certain to hold your air conditioning unit clean.
  4. Clean floors with a damp rag or mop, rather than dry-dusting or sweeping.

Exposure to pets

  1. If you are allergic to a household pet, hold the animal out of your home as much as possible. If the pet must be inside, hold it out of the bedroom so you are not exposed to animal allergens while you sleep.
  2. Wash your hands immediately after petting any animals; wash your clothes after visiting friends with pets.
  3. Close the air ducts to your bedroom if you own forced-air or central heating or cooling.

    Replace carpeting with hardwood, tile or linoleum, every of which are easier to hold dander-free.

Treatments that are not recommended for allergic rhinitis

  1. Antibiotics: Effective for the treatment of bacterial infections, antibiotics do not affect the course of uncomplicated common colds (a viral infection) and are of no benefit for noninfectious rhinitis, including allergic rhinitis.
  2. Nasal surgery: Surgery is not a treatment for allergic rhinitis, but it may assist if patients own nasal polyps or chronic sinusitis that is not responsive to antibiotics or nasal steroid sprays.

1.

Nelson HS, Rachelefsky GS, Bernick J. The Allergy Report. Milwaukee, Wis.: American Academy of Allergy, Asthma & Immunology; 2000….

2. Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen).

What is the best allergy medicine for indoor and outdoor allergies

Allergy. 2008;63(suppl 86):8–160.

3. Bousquet J, Van Cauwenberge P, Khaltaev N; ARIA Workshop Group; World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol. 2001;108(5 suppl):S147–S334.

4. Price D, Bond C, Bouchard J, et al. International Primary Care Respiratory Group (IPCRG) Guidelines: management of allergic rhinitis. Prim Care Respir J.

2006;15(1):58–70.

5. Scadding GK, Durham SR, Mirakian R, et al. British Society for Allergy and Clinical Immunology. BSACI guidelines for the management of allergic and non-allergic rhinitis. Clin Exp Allergy. 2008;38(1):19–42.

6. Plaut M, Valentine MD. Clinical practice. Allergic rhinitis. N Engl J Med. 2005;353(18):1934–1944.

7. Wallace DV, Dykewics MS, Bernstein DI, et al. The diagnosis and management of rhinitis: an updated practice parameter [published correction appears in J Allergy Clin Immunol.

2008;122(6):1237]. J Allergy Clin Immunol. 2008;122(2 suppl):S1–S84.

8. Calderon MA, Alves B, Jacobson M, Hurwitz B, Sheikh A, Durham S. Allergen injection immunotherapy for seasonal allergic rhinitis. Cochrane Database Syst Rev. 2007;(1):CD001936.

9. Derendorf H, Meltzer EO. Molecular and clinical pharmacology of intra-nasal corticosteroids: clinical and therapeutic implications. Allergy. 2008;63(10):1292–1300.

10. Weiner JM, Abramson MJ, Puy RM. Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systematic review of randomised controlled trials.

BMJ. 1998;317(7173):1624–1629.

11. Ratner PH, van Bavel JH, Martin BG, et al. A comparison of the efficacy of fluticasone propionate aqueous nasal spray and loratadine, alone and in combination, for the treatment of seasonal allergic rhinitis. J Fam Pract. 1998;47(2):118–125.

12. Yáñez A, Rodrigo GJ. Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis.

What is the best allergy medicine for indoor and outdoor allergies

Ann Allergy Asthma Immunol. 2002;89(5):479–484.

13. Kaszuba SM, Baroody FM, deTineo M, Haney L, Blair C, Naclerio RM. Superiority of an intranasal corticosteroid compared with an oral antihistamine in the as-needed treatment of seasonal allergic rhinitis. Arch Intern Med. 2001;161(21):2581–2587.

14. Waddell AN, Patel SK, Toma AG, Maw AR. Intranasal steroid sprays in the treatment of rhinitis: is one better than another? J Laryngol Otol. 2003;117(11):843–845.

15.

Demoly P. Safety of intranasal corticosteroids in acute rhinosinusitis. Am J Otolaryngol. 2008;29(6):403–413.

16. Lumry WR. A review of the preclinical and clinical data of newer intra-nasal steroids used in the treatment of allergic rhinitis. J Allergy Clin Immunol. 1999;104(4 pt 1):S150–S158.

17. Schenkel EJ, Skoner DP, Bronsky EA, et al. Absence of growth retardation in children with perennial allergic rhinitis after one year of treatment with mometasone furoate aqueous nasal spray.

Pediatrics.

What is the best allergy medicine for indoor and outdoor allergies

2000;105(2):E22.

18. Mansfield LE, Mendoza CP. Medium and long-term growth in children receiving intranasal beclomethasone dipropionate: a clinical experience. South Med J. 2002;95(3):334–340.

19. Skoner DP, Rachelefsky GS, Meltzer EO, et al. Detection of growth suppression in children during treatment with intranasal beclomethasone dipropionate. Pediatrics. 2000;105(2):E23.

20. Wilson AM, McFarlane LC, Lipworth BJ. Effects of repeated once daily dosing of three intranasal corticosteroids on basal and dynamic measures of hypothalamic-pituitary-adrenal-axis activity.

J Allergy Clin Immunol. 1998;101(4 pt 1):470–474.

21. Alexander S. The pharmacology & biochemistry of histamine receptors. August 1996. http://www.nottingham.ac.uk/~mqzwww/histamine.html. Accessed November 19, 2009.

22. Bender BG, Berning S, Dudden R, Milgrom H, Tran ZV. Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis. J Allergy Clin Immunol. 2003;111(4):770–776.

23.

Verster JC, Volkerts ER. Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic [published corrections appear in Ann Allergy Asthma Immunol. 2004;92(6):675, and Ann Allergy Asthma Immunol. 2005;94(3):409–410]. Ann Allergy Asthma Immunol. 2004;92(3):294–303.

24. Robb G, Sultana S, Ameratunga S, Jackson R. A systematic review of epidemiological studies investigating risk factors for work-related road traffic crashes and injuries. Inj Prev. 2008;14(1):51–58.

25. Kay GG, Quig ME.

Impact of sedating antihistamines on safety and productivity. Allergy Asthma Proc. 2001;22(5):281–283.

26. Bender BG, McCormick DR, Milgrom H. Children’s school performance is not impaired by short-term istration of diphenhydramine or loratadine. J Pediatr. 2001;138(5):656–660.

27. Lipworth BJ, Jackson CM. Safety of inhaled and intranasal corticosteroids: lessons for the new millennium. Drug Saf. 2000;23(1):11–33.

28. Corren J, Storms W, Bernstein J, Berger W, Nayak A, Sacks H; Azelastine Cetirizine Trial No.

1 (ACT 1) Study Group. Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis. Clin Ther. 2005;27(5):543–553.

29. Berger WE, White MV; Rhinitis Study Group. Efficacy of azelastine nasal spray in patients with an unsatisfactory response to loratadine. Ann Allergy Asthma Immunol. 2003;91(2):205–211.

30. Graf P, Enerdal J, Hallén H. Ten days’ use of oxymetazoline nasal spray with or without benzalkonium chloride in patients with vasomotor rhinitis.

Arch Otolaryngol Head Neck Surg. 1999;125(10):1128–1132.

31. Coates ML, Rembold CM, Farr BM. Does pseudoephedrine increase blood pressure in patients with controlled hypertension? J Fam Pract. 1995;40(1):22–26.

32. Grainger J, Drake-Lee A. Montelukast in allergic rhinitis: a systematic review and meta-analysis. Clin Otolaryngol. 2006;31(5):360–367.

33. Mucha SM, deTineo M, Naclerio RM, Baroody FM.

Comparison of montelukast and pseudoephedrine in the treatment of allergic rhinitis. Arch Otolaryngol Head Neck Surg. 2006;132(2):164–172.

34. Wilson AM, O’Byrne PM, Parameswaran K. Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis. Am J Med. 2004;116(5):338–344.

35. Juniper EF, Kline PA, Hargreave FE, Dolovich J. Comparison of beclomethasone dipropionate aqueous nasal spray, astemizole, and the combination in the prophylactic treatment of ragweed pollen-induced rhinoconjunctivitis.

J Allergy Clin Immunol.

What is the best allergy medicine for indoor and outdoor allergies

1989;83(3):627–633.

36. Barnes ML, Ward JH, Fardon TC, Lipworth BJ. Effects of levocetirizine as add-on therapy to fluticasone in seasonal allergic rhinitis. Clin Exp Allergy. 2006;36(5):676–684.

37. Di Lorenzo G, Pacor ML, Pellitteri ME, et al. Randomized placebo-controlled trial comparing fluticasone aqueous nasal spray in monotherapy, fluticasone plus cetirizine, fluticasone plus montelukast and cetirizine plus montelukast for seasonal allergic rhinitis [published correction appears in Clin Exp Allergy. 2004;34(8):1329]. Clin Exp Allergy. 2004;34(2):259–267.

38. Ratner PH, Hampel F, Van Bavel J, et al. Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis.

Ann Allergy Asthma Immunol. 2008;100(1):74–81.

39. Durham SR, Yang WH, Pedersen MR, Johansen N, Rak S. Sublingual immunotherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol. 2006;117(4):802–809.

40. Bousquet J, Khaltaev N. Global Surveillance, Prevention and Control of Chronic Respiratory Diseases: A Comprehensive Approach.

Geneva: World Health Organization; 2007.

41. Dahl R, Kapp A, Colombo G, et al. Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhino-conjunctivitis. J Allergy Clin Immunol. 2006;118(2):434–440.

42. Compalati E, Penagos M, Tarantini F, Passalacqua G, Canonica GW. Specific immunotherapy for respiratory allergy: state of the art according to current meta-analyses. Ann Allergy Asthma Immunol. 2009;102(1):22–28.

43. Pauli G, Larsen TH, Rak S, et al. Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis [published correction appears in J Allergy Clin Immunol.

2009;123(1):166]. J Allergy Clin Immunol. 2008;122(5):951–960.

44. Casale TB, Condemi J, LaForce C, et al.; Omalizumab Seasonal Allergic Rhinitis Trial Group. Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial. JAMA. 2001;286(23):2956–2967.

45. Red Book. Montvale, N.J.: Medical Economics Data; 2007.

46. Ng DK, Chow PY, Ming SP, et al. A double-blind, randomized, placebo-controlled trial of acupuncture for the treatment of childhood persistent allergic rhinitis.

Pediatrics. 2004;114(5):1242–1247.

47. Xue CC, English R, Zhang JJ, Da Costa C, Li CG. Effect of acupuncture in the treatment of seasonal allergic rhinitis: a randomized controlled clinical trial. Am J Chin Med. 2002;30(1):1–11.

48. Brinkhaus B, Witt CM, Jena S, Liecker B, Wegscheider K, Willich SN. Acupuncture in patients with allergic rhinitis: a pragmatic randomized trial. Ann Allergy Asthma Immunol. 2008;101(5):535–543.

49. Roberts J, Huissoon A, Dretzke J, Wang D, Hyde C. A systematic review of the clinical effectiveness of acupuncture for allergic rhinitis. BMC Complement Altern Med. 2008;8:13.

50.

Kuitunen M, Kukkonen K, Juntunen-Backman K, et al. Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the entire cohort. J Allergy Clin Immunol. 2009;123(2):335–341.

51. Vliagoftis H, Kouranos VD, Betsi GI, Falagas ME. Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials. Ann Allergy Asthma Immunol.

2008;101(6):570–579.

52. Schapowal A; Petasites Study Group. Randomised controlled trial of butterbur and cetirizine for treating seasonal allergic rhinitis. BMJ. 2002;324(7330):144–146.

53. Pynnonen MA, Mukerji SS, Kim HM, Adams ME, Terrell JE. Nasal saline for chronic sinonasal symptoms: a randomized controlled trial.

What is the best allergy medicine for indoor and outdoor allergies

Arch Otolaryngol Head Neck Surg. 2007;133(11):1115–1120.

54. Koopman LP, van Strien RT, Kerkhof M, et al.; Prevention and Incidence of Asthma and Mite Allergy (PIAMA) Study. Placebo-controlled trial of home dust mite-impermeable mattress covers: effect on symptoms in early childhood. Am J Respir Crit Care Med. 2002;166(3):307–313.

55. Terreehorst I, Hak E, Oosting AJ, et al. Evaluation of impermeable covers for bedding in patients with allergic rhinitis.

N Engl J Med. 2003;349(3):237–246.

56. Sheikh A, Hurwitz B, Shehata Y. Home dust mite avoidance measures for perennial allergic rhinitis. Cochrane Database Syst Rev. 2007;(1):CD001563.

57. Zutavern A, Brockow I, Schaff B, et al.; LISA Study Group. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA. Pediatrics. 2008;121(1):e44–e52.

58. Greer FR, Sicherer SH, Burks AW; American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on Allergy and Immunology.

Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics. 2008;121(1):183–191.

59. Kramer MS, Matush L, Vanilovich I, et al.; Promotion of Breastfeeding Intervention Trial (PROBIT) Study Group. Effect of prolonged and exclusive breast feeding on risk of allergy and asthma: cluster randomised trial.

BMJ. 2007;335(7624):815.

60. Kilburn S, Lasserson TJ, McKean M. Pet allergen control measures for allergic asthma in children and adults. Cochrane Database Syst Rev. 2003;(1):CD002989.

61. Wood RA, Johnson EF, Van Natta ML, Chen PH, Eggleston PA. A placebo-controlled trial of a HEPA air cleaner in the treatment of cat allergy. Am J Respir Crit Care Med. 1998;158(1):115–120.


Common allergens

The most common allergen is pollen, a powder released by trees, grasses and weeds that fertilize the seeds of neighboring plants.

As plants rely on the wind to do the work for them, the pollination season sees billions of microscopic particles fill the air, and some of them finish up in people’s noses and mouths.

Spring bloomers include ash, birch, cedar, elm and maple trees, plus numerous species of grass. Weeds pollinate in the tardy summer and drop, with ragweed being the most volatile.

The pollen that sits on brightly colored flowers is rarely responsible for hay fever because it is heavier and falls to the ground rather than becoming airborne. Bees and other insects carry flower pollen from one flower to the next without ever bothering human noses.

Mold allergies are diverse.

Mold is a spore that grows on rotting logs, dead leaves and grasses. While dry-weather mold species exist, numerous types of mold thrive in moist, rainy conditions, and release their spores overnight. During both the spring and drop allergy seasons, pollen is released mainly in the morning hours and travels best on dry, warm and breezy days.


Pollen count

How do scientists know how much pollen is in the air? They set a trap. The trap — generally a glass plate or rod coated with adhesive — is analyzed every few hours, and the number of particles collected is then averaged to reflect the particles that would pass through the area in any 24-hour period.

That measurement is converted to pollen per cubic meter. Mold counts work much the same way.

A pollen count is an imprecise measurement, scientists confess, and an arduous one — at the analysis stage, pollen grains are counted one by one under a microscope. It is also highly time-consuming to discern between types of pollen, so they are generally bundled into one variable. Given the imprecise nature of the measurement, entire daily pollen counts are often reported simply as low, moderate or high.

The American Academy of Allergy, Asthma & Immunology provides up-to-date pollen counts for U.S.

states.


RELATED VIDEO: