Dust mite questions and answers, HouseDustMite.com, henta 26. februar 2018
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Stewart GA, Kollinger MR, King CM, Thompson PJ. A comparative study of three serine proteases from Dermatophagoides pteronyssinus and D. farinae. Allergy 1994;49(7):553-60
Thomas WR, Smith WA, Hales BJ. The allergenic specificities of the home dust mite. Chang Gung Med J 2004;27(8):563-9.
Li CS, Hsu CW, Chua KY, Hsieh KH, Lin RH. Environmental distribution of home dust mite allergen (Der p 5). J Allergy Clin Immunol 1996;97(3):857-9
Aki T, Kodama T, Fujikawa A, Miura K, Shigeta S, Wada T, Jyo T, Murooka Y, Oka S, Ono K.
Immunochemical characterization of recombinant and native tropomyosins as a new allergen from the home dust mite. J Allergy Clin Immunol 1995;96(1):74-83
Tsai LC, Chao PL, Shen HD, Tang RB, Chang TC, Chang ZN, Hung MW, Lee BL, Chua KY. Isolation and characterization of a novel 98- kd Dermatophagoides farinae mite allergen. J Allergy Clin Immunol 1998;102(2):295-303
Fujikawa A, Uchida K, Yanagidani A, Kawamoto S, Aki T, Shigeta S, Wada T, Suzuki O, Jyo T, Ono K. Altered antigenicity of M-177, a 177-kDa allergen from the home dust mite Dermatophagoides farinae, in stored extract.
Clin Exp Allergy 1998;28(12):1549-58
Epton MJ, Smith W, Hales BJ, Hazell L, Thompson PJ, Thomas WR. Non-allergenic antigen in allergic sensitization: responses to the mite ferritin heavy chain antigen by allergic and non-allergic subjects. Clin Exp Allergy 2002;32(9):1341-7
Gehring U, Brunekreef B, Fahlbusch B, Wichmann HE, Heinrich J; the INGA study group. Are home dust mite allergen levels influenced by freezing winter weather? Allergy 2005;60(8):1079-82 King C, Simpson RJ, Moritz RL, Reed GE, Thompson PJ, Stewart GA. The isolation and characterization of a novel collagenolytic serine protease allergen (Der p 9) from the dust mite Dermatophagoides pteronyssinus.
J Allergy Clin Immunol 1996;98:739-47
Li CS, Hsu CW, Lin RH. Home dust mite allergens (Der p I and Der p V) within domestic environments of atopic and control children.
Arch Environ Health 1997;52(3):208-12 Trakultivakorn M, Nuglor T. Sensitization to Dermatophagoides pteronyssinus and Blomia tropicalis extracts and recombinant mite allergens in atopic Thai patients. Asian Pac J Allergy Immunol 2002;20(4):217-21
Hales BJ, Shen HD, Thomas WR. Crossreactivity of T-cell responses to Dermatophagoides pteronyssinus and D. farinae. Studies with group 1 and 7 allergens. Clin Exp Allergy 2000;30(7):927-33 Takai T, Kato T, Yasueda H, Okumura K, Ogawa H. Analysis of the structure and allergenicity of recombinant pro- and mature Der p 1 and Der f 1: Major conformational IgE epitopes blocked by prodomains. J Allergy Clin Immunol 2005;115(3):555-63
Meno K, Thorsted PB, Ipsen H, Kristensen O, Larsen JN, Spangfort MD, Gajhede M, Lund K.
The crystal structure of recombinant proDer p 1, a major home dust mite proteolytic allergen. J Immunol 2005;175(6):3835-45
de HS, Stura E, VanderElst L, Carlier V, Jacquemin M, Saint-Remy JM. Threedimensional structure and IgE-binding properties of mature fully athletic Der p 1, a clinically relevant major allergen. J Allergy Clin Immunol 2006;117(3):571-576
Guler N, Kirerleri E, Tamay Z, Ones U. Atopy patch testing in children with asthma and rhinitis symptoms allergic to home dust mite.
Pediatr Allergy Immunol 2006;17(5):346-50
Garcia-Gonzalez JJ, Vega-Chicote JM, Rico P, del Prado JM, et al. Prevalence of atopy in students from Malaga, Spain. Ann Allergy Asthma Immunol 1998;80(3):237-44
Tsai JJ, Chen WC. Diverse age of asthmatic patients affected by diverse aeroallergens.
Restani P, Gaiaschi A, Plebani A, Beretta B, Cavagni G, Fiocchi A, Poiesi C, Velona T, Ugazio AG, Galli CL (1999) Cross- reactivity between milk proteins from diverse animal species Clin Exp Allergy 29:997-1004
Ylitalo L, Mákinen-Kiljunen S, Turjanmaa K, Palosuo T, Reunala T (1999) Cow’s milk casein, a hidden allergen in natural rubber latex gloves J Allergy Clin Immunol 104:177-80
Epidermals / Animal Proteins [top]
Kauppinen J, Zeiler T, Rautiainen J, Rytkönen-Nissinen M, Taivainen A, Mäntyjärvi R, Virtanen T (1999) Mutant derivatives of the main respiratory allergen of cow are less allergenic than the intact molecule Clin Exp Allergy 29:989-96
McSharry C, MacLeod K, McGregor S, Speekenbrink ABJ, Sriram S, Boyd F, Boyd G (1999) Mucosal immunity in extrinsic allergic alveolitis: salivary immunoglobulins and antibody against inhaled avian antigens among pigeon breeders Clin Exp Allergy 29:957-64
Plaschke P, Janson C, Norrman E, Bjórnsson E, Ellbjár S, Járvholm B (1999) Association between atopic sensitization and asthma and bronchial hyperresponsiveness in Swedish adults: Pets, and not mites, are the most significant allergens J Allergy Clin Immunol 104:58-65
Fish / Fowl / Meat [top]
Kelso JM, Cockrell GE, Helm RM, Burks AW (1999) Common allergens in avian meats J Allergy Clin Immunol 104:202-4
House Dust / Mites [top]
Holm L, van Hage-Hamsten M, Öhman S, Scheynius A (1999) Sensitization to allergens of house-duste mite in adults with atopic dermatitis in a freezing temperate region Allergy 54:708-15
Nakada M, Nishizaki K, Yoshino T, Okano M, Yamamoto T, Masuda Y, Ohta N, Akagi T (1999) CD80 (B7-1) and CD86 (B7-2) antigens on home dust mite-specific T cells in atopic disease function through T-T cell interactions J Allergy Clin Immunol 104:222-7
Wan H, Winton HL, Soeller C, Tovey ER, Gruenert DC, Thompson PJ, Stewart GA, Taylor GW, Garrod DR, Cannell MB, Robinson C (1999) Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions J Clin Invest 104 (1):123-133
Gutgesell C, Seubert A, Junghans V, Neumann C (1999) Inverse correlation of domestic exposure to Dermatophagoides pteronyssinus antigen patch test reactivity in patients with atopic dermatitis Clin Exp Allergy 29:920-5
Puerta L, Kennedy MW, Jiménez S, Caraballo L (1999) Structural and Ligand Binding Analysis of Recombinant Blo t 13 Allergen from Blomia tropicalis Mite, a Fatty Acid Binding Protein Int Arch Allergy Immunol119:181-4
Engelhart ST, Wilmes-Link M, Gilges S, Exner M, Kramer MH (1999) Exposure of submarine personnel to home dust mite allergens J Allergy Clin Immunol 104:242
Marcos Bravo C, Luna Ortiz I, Outon Soto A, Gonzalez Vazquez R (1999) Allergy to storage mites Allergy 54:769
Chew FT, Yi FC, Chua KY, Fernandez-Caldas E, Arruda LK, Chapman MD, Lee BW (1999) Allergenic differences between the domestic mites Blomia tropicalis and Dermatophagoides pteronyssinus Clin Exp Allergy 29:982-8
Warner A, Boström S, Möller C, Kjellman NIM (1999) Mite fauna in the home and sensitivity to house-dust and storage mites Allergy 54:681-90
Yu CK, Shieh CM, Lei HY (1999) Repeated intratracheal inoculation of home dust mite (Dermatophagoides farinae) induces pulmonary eosinophilic inflammation and IgE antibody production in mice J Allergy Clin Immunol 104:228-36
Insects / Venoms [top]
Irsch, J, König C, Löhndorf A, Tesch H, Krieg T, Merk H, Radbruch A, Hunzelmann N (1999) The frequency of phospholipase A2 binding of basophilic granulocytes does not decrease during bee- venom- specific immunotherapy Allergy 54:742-7
Jung K, Lehmann B, Linse R (1999) Role of immunoblotting for diagnosis of insect venom allergy Allergologie 22:426-32 (in German)
Mushroom / Mould / Yeast / Parasites [top]
Aden E, Weber B, Bossert J, Teppke M, Candid E, Wahl R, Fiebig H, Cromwell O (1999) Standardization of Alternaria alternata: Extraction and quantification of Alt a 1 by using an mAb-based 2-site binding assay J Allergy Clin Immunol 104:128-35
Doekes G, Kamminga N, Helwegen L, Heederik D (1999) Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger Occup Environ Med 56(7):454-9
Ricaurté KK, Greenberger PA, Fullerton DA (1999) Allergic bronchopulmonary aspergillosis with multiple Streptococcus pneumoniae lung abscesses: An unusual initial case presentation J Allergy Clin Immunol 104:238-9
Fruit / Vegetables / Latex [top]
Chardin H, Desvaux FX, Mayer C, Sénéchal H, Peltre G (1999) Protein and Allergen Analysis of Latex Mattresses Int Arch Allergy Immunol119:239-46
Cheng L, Lee D (1999) Review of latex allergy J Am Board Fam Pract 12(4):285-92
Grains / Grass Pollen / Tree Pollen [top]
Klimek L, Reichenbach M, Mann W (1999) Natural pollen exposition influences sICAM-1 in nasal secretions in birch pollen-allergic rhinitis Allergologie 22:397-403 (in German)
Lovborg U, Baker PJ, Taylor DJM, Yin P, Tovey ER (1999) Subtribe- specific monoclonal antibodies to Lolium perenneClin Exp Allergy 29:973-81
Sone T, Morikubo K, Shimizu K, Komiyama N, Tsunoo H, Kino K (1999) Peptide Specificity, HLA Class II Restriction, and T-Cell Subsets of the T-Cell Clones Specific to Either Weep j 1 or Weep j 2, the Major Allergens of Japanese Cedar (Cryptomeria japonica) Pollen Int Arch Allergy Immunol 119:185-96
Brewczynski PZ, Kroon AM (1999) Efficacy and safety of immunotherapy with modified grasspollen allergens.
Results of a placebo-controlled study Allergologie 22:411-20 (in German)
Hänninen AR, Mikkola JH, Kalkkinen N, Turjanmaa K, Ylitalo L, Reunala T, Palosuo T (1999) Increased allergen production in turnip (Brassica rapa) by treatments activating defense mechanisms J Allergy Clin Immunol 104:194-201
Würtzen PA, Wissenbach M, Ipsen H, Bufe A, Arnved J, van Neerven RJJ (1999) Highly heterogeneous Phl p 5-specific T cells from patients with allergic rhinitis differentially recognize recombinant Phl p 5 isoallergens J Allergy Clin Immunol 104:115-22
Hill DJ, Heine RG, Cameron DJS, Francis DEM, Bines JE (1999) The natural history of intolerance to soy and extensively hydrolyzed formula in infants with multiple food protein intoleranceJ Pediatr 135:118-21
Lallès JP, Tukur HM, Salgado P, Mills ENC , Morgan MRA, Quillien L, Levieux D, Toullec R (1999) Immunochemical Studies on Gastric and Intestinal Digestion of Soybean Glycinin and beta- Conglycininin Vivo J Agric Food Chem 47:2797-806
Sicherer SH, Furlong TJ, De Simone J, Sampson HA (1999) Self-reported allergic reactions to peanut on commercial airliners J Allergy Clin Immunol 104:186-9
Seeds / Nuts [top]
Beyer AV, Gall H, Peter RU (1999) Immediate-type hypersensitivity to vanilla Allergologie 22:433-6 (in German)
Chemicals / Drugs / Food Additives [top]
Gücüyener K, Türktas I, Serdaroglu A, Ezgü FS (1999) Suspected allergy to lamotrigine Allergy 54:767
Shoji T, Yoshida S, Sakamoto H, Hasegawa H, Nakagawa H, Amayasu H (1999) Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma Clin Exp Allergy 29:950-6
Szczeklik A, Stevenson DD (1999) Aspirin-induced asthma: Advances in pathogenesis and management [review] J Allergy Clin Immunol 104:5-13
Alfaya T, Pulido Z, Gonzalez-Mancebo E, Cuevas M, Quirce S, de la Hoz B (1999) Anaphylaxis to trimethoprim Allergy 54:766
von Greyerz S, Burkhart C, Pichler WJ (1999) Molecular Basis of Drug Recognition by Specific T-Cell Receptors [review] Int Arch Allergy Immunol119:173-80
Antico A, Soana R (1999) Chronic allergic-like dermatopathies in nickel-sensitive patients.
Results of dietary restrictions and challenge with nickel salts Allergy Asthma Proc 20(4):235-42
Brockow K, Vieluf D, Púschel K, Grosch J, Ring J (1999) Increased postmortem serum mast cell tryptase in a fatal anaphylactoid reaction to nonionic radiocontrast medium J Allergy Clin Immunol 104:237
Wicki J, Deluze C, Cirafici L, Desmeules J (1999) Anaphylactic shock induced by intraurethral use of chlorhexidine Allergy 54:768
Environmental Contaminants [top]
General Topics / Other [top]
Miadonna A, Milazzo N, Gibelli S, Salmaso C, Lorini M, Tedeschi A (1999) Nasal response to a single antigen challenge in patients with allergic rhinitis — inflammatory cell recruitment persists up to 48 hours Clin Exp Allergy 29:941-9
Rabinovitch N, Gelfand EW, Leung DYM (1999) The role of immunoglobulin therapy in allergic diseases Allergy 54:662-8
Shadick NA, Liang MH, Partridge AJ, Bingham C, Wright E, Fossel AH, Sheffer AL (1999) The natural history of exercise-induced anaphylaxis: Survey results from a 10-year follow-up study J Allergy Clin Immunol 104:123-7
Jung T, Moessner R, Dieckhoff K, Heidrich S, Neumann C (1999) Mechanisms of deficient interferon- gamma production in atopic diseases Clin Exp Allergy 29:912-19
Kodama A, Horikawa T, Suzuki T, Ajiki W, Takashima T, Harada S, Ichihashi M (1999) Effect of stress on atopic dermatitis: Investigation in patients after the Grand Hanshin Earthquake J Allergy Clin Immunol 104:173-6
Ohta K, Yamashita N (1999) Apoptosis of eosinophils and lymphocytes in allergic inflammation J Allergy Clin Immunol 104:14-21
Kimber I, Gerberick GF, Basketter DA (1999) Thresholds in contact sensitization: theoretical and practical considerations Food Chem Toxicol 37:553-560
Borger P, Jonker GJ, Vellenga E, Postma DS, De Monchy JGR, Kaufmann HF (1999) Allergen challenge primes for IL-5 mRNA production and abrogates beta- adrenergic function in peripheral blood T lymphocytes from asthmatics Clin Exp Allergy 29:933-40
Tassabehji M, Römer U, Hauswald B, Hüttenbrink KB (1999) Determination of provocation threshold of the nasal provocation test (NPT) in patients with allergic rhinitis Allergologie 22:404-10 (in German)
Piacentini GL, Peterson C, Peroni DG, Bodini A, Boner AL (1999) Allergen avoidance at high altitude and urinary eosinophil protein X J Allergy Clin Immunol 104:243-4
Sherrill D, Stein R, Kurzius-Spencer M, Martinez F (1999) On early sensitization to allergens and development of respiratory symptoms Clin Exp Allergy 29:905-11
Shimada Y, Sato S, Hasegawa M, Tedder TF, Takehara K (1999) Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: Soluble L-selectin levels indicate disease severity J Allergy Clin Immunol 104:163-8
Ludolph-Hauser D, Przybilla B (1999) Mast cell tryptase and chymase mediators in skin diseases [review] Allergologie 22:421-5 (in German)
Valenta R, Lidholm J, Niederberger V, Hayek B, Kraft D, Grönlund H (1999) The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT) [review] Clin Exp Allergy 29:896-904
ErbKJ (1999) Atopic disorders: a default pathway in the absence of infection?
[Viewpoint] Immunol Today 20:317-22
Hauk PJ, Wenzel SE, Trumble AE, Szefler SJ, Leung DYM (1999) Increased T-cell receptor V beta 8+ T cells in bronchoalveolar lavage fluid of subjects with poorly controlled asthma: A potential role for microbial superantigens J Allergy Clin Immunol 104:37-45
Sherrill DL, Stein R, Halonen M, Holberg CJ, Wright A, Martinez FD (1999) Total serum IgE and its association with asthma symptoms and allergic sensitization among children J Allergy Clin Immunol 104:28-36
Nusam D, Geva A, Kalderon I, Cohen S (1999) Intravaginal desensitization to seminal fluid Allergy 54:765
Becker EL (1999) Elements of the history of our present concepts of anaphylaxis, hay fever and asthma [review] Clin Exp Allergy 29:875-95
Rinn K, Schiffman K, Otero HO, Disis ML (1999) Antigen-specific recall urticaria to a peptide-based vaccine J Allergy Clin Immunol 104:240-1
Rohrbach M, Frey U, Kraemer R, Liechti-Gallati S (1999) A variant in the gene for GM-CSF, I117T, is associated with atopic asthma in a Swiss population of asthmatic children J Allergy Clin Immunol 104:247-
Grouhi M, Alshehri M, Hummel D, Roifman CM (1999) Anaphylaxis and epinephrine auto-injector training: Who will teach the teachers?
J Allergy Clin Immunol 104:190-3
Ferrer M, Nakazawa K, Kaplan AP (1999) Complement dependence of histamine release in chronic urticaria J Allergy Clin Immunol 104:169-72
Wiedermann U, Jahn-Schmid B, Lindblad M, Rask C, Holmgren J, Kraft D, Ebner C (1999) Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy Int Immunol 11:1131-8
After informed consent, subjects will be randomly assigned to ILIT group or placebo group in double-blind manner.
In both group, causal allergen or placebo will be injected into inguinal lymph node through guidance by ultrasonography three times with 4-week interval. In ILIT group, initial dose of allergen will be 1,000-fold diluted solution from maximal concentration of allergen extract for subcutaneous immunotherapy (Tyrosine S, Allergy Therapeutic, West Sussex, UK) in volume of 0.1ml. If skin is highly reactive in skin prick test, the initial dose will be 10-fold dilution from maximal concentration where diameter of wheal is less than that of histamine.
After the first dose, allergen concentration will be escalated 3-fold at second dose, and 10-fold at third dose if there are no (or mild) local or systemic hypersensitivity reaction. The allergen concentration will not change at second or third dose if there is moderate local or systemic reaction. The allergen concentration will decrease by 10 or 100-fold from previous concentration or further injection will be held if there is severe local or systemic reaction after sufficient explanation and discussion with subjects.
The investigators will assess allergic rhinitis symptom score before and 4, 12 months after the initial treatment.
Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) and Sino-Nasal Outcome Test (SNOT-20) will be used. Visual analogue scale (VAS) of symptoms including rhinorrhea, sneezing, nasal obstruction, postnasal drip, eye/nose/ear/palate itching, dyspnea, wheezing, chest discomfort as well as urticaria, angioedema, and itching on exposed skin during exposure to causal allergen in daily life will be also evaluated. Skin prick test (SPT), intradermal test (IDT), blood sampling for serum entire immunoglobulin E (IgE), allergen-specific IgE, and allergen-specific immunoglobulin G4 (IgG4), nasal lavage for Th1, Th2, and Treg cytokines, and nasal provocation test (NPT) with Df and/or Dp allergen (in subjects whose AR symptoms are provoked by Df and/or Dp) will be also performed before and 4, 12 months after the initial treatment.
In addition, the investigators evaluated the change of subjects’ recognition of causal allergens, their avoidance, and AIT during this study. Using VAS, subjects were requested to score the rate of agreement with "Allergen provokes allergic symptoms in daily life", "Allergen avoidance can reduce allergic symptoms", "Allergen-specific Immunotherapy (AIT) can reduce allergic symptoms", "I can pay 50,000 Korean Won (KRW)/month for allergen avoidance", "I can pay 100,000 KRW/month for allergen avoidance", "I can pay 200,000 KRW/month for allergen avoidance", "I can pay 150,000 KRW for each injection of ILIT", "I can pay 300,000 KRW for each injection of ILIT", "I can pay 600,000 KRW for each injection of ILIT" before and after SPT/IDT, after NPT, 4 months and 1 year after ILIT.
Adverse events will be recorded and graded according to Muller classification and Ring and Meissner classification.