What can i take for allergies while breastfeeding

Cows’ milk allergy can cause a wide range of symptoms, including:

  1. digestive problems – such as stomach ache, vomiting, colic, diarrhoea or constipation
  2. hay fever-like symptoms – such as a runny or blocked nose
  3. skin reactions – such as a red itchy rash or swelling of the lips, face and around the eyes
  4. eczema that does not improve with treatment

Occasionally CMA can cause severe allergic symptoms that come on suddenly, such as swelling in the mouth or throat, wheezing, cough, shortness of breath, and difficult, noisy breathing.

A severe allergic reaction, or anaphylaxis, is a medical emergency – call 999 or go immediately to your local hospital A&E department.


Further information

Always consult your healthcare provider to ensure the information displayed on this sheet applies to your personal circumstances.

Medical Disclaimer

If you ponder your baby is having a reaction to cows’ milk, see your GP to discuss your concerns.

They will be capable to assess if your baby’s symptoms may be caused by a cows’ milk allergy or something else. Make certain you get medical advice before taking cows’ milk out of your child’s diet as it contains significant nutrients.


istrative Information

LactMed Record Number

163

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment.

You should consult your healthcare provider for breastfeeding advice related to your specific situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.


Loratadine Identification

CAS Registry Number

79794-75-5

Substance Name

Loratadine

Drug Class

Breast Feeding

Lactation

Antihistamines

Nonsedating Antihistamines



Loratadine use while Breastfeeding

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Medically reviewed by Drugs.com.

What can i take for allergies while breastfeeding

Final updated on Jul 13, 2019.


Cows’ milk allergy in babies

Cows’ milk allergy (CMA), also called cows’ milk protein allergy, is one of the most common childhood food allergies. It is estimated to affect around 7% of babies under 1, though most children grow out of it by the age of 5.

CMA typically develops when cows’ milk is first introduced into your baby’s diet either in formula or when your baby starts eating solids.

More rarely, it can affect babies who are exclusively breastfed because of cows’ milk from the mother’s diet passing to the baby through breast milk.

There are 2 main types of CMA:

  1. immediate CMA – where symptoms typically start within minutes of having cows’ milk
  2. delayed CMA – where symptoms typically start several hours, or even days, after having cows’ milk


Loratadine Levels and Effects while Breastfeeding

Effects in Breastfed Infants

A survey of 51 mothers who took loratadine during breastfeeding between 1999 and 2001 was conducted by a teratogen information service.

Most of the infants were over 2 months ancient and loratadine was generally taken for one week or less. Two mothers reported minor sedation in their infants, one at 3 days of age and one at 3 months of age. Both mothers were taking a dose of 10 mg daily. Weight acquire and psychomotor development were similar to infants in a control group of breastfed infants unexposed to medications.[3] An extension of the study that compared the results of this study (plus one additional patient) to that of a control group of 88 mothers who took a drug known to be safe while breastfeeding.

No differences in sedation or any other side effects (p=0.606) in the baby were found between mothers who took loratadine during breastfeeding and those of the control group.[4]

Alternate Drugs to Consider

Desloratadine, Fexofenadine

Drug Levels

After a single oral dose of 40 mg of loratadine in 6 women, average peak milk levels of 29.2 (range 20.4 to 39) mcg/L occurred at two hours after the dose. In addition, average desloratadine peak milk levels of 16 (range 9 to 29.6) mcg/L occurred at 5.3 hours after the dose. The entire quantity excreted in milk over 48 hours was 11.7 mcg of loratadine and its metabolite.

However, the dose istered was four times greater than the usual dose of the drug, so a entire dose of about 3 mcg would be expected with a 10 mg dose. The calculated average and maximum expected doses of loratadine plus desloratadine in milk were 0.46 and 1.1% and of the maternal weight-adjusted dose, respectively, after the 40 mg dose.[2]

Summary of Use during Lactation

Because of its lack of sedation and low milk levels, maternal use of loratadine would not be expected to cause any adverse effects in breastfed infants.

Loratadine might own a negative effect on lactation, especially in combination with a sympathomimetic agent such as pseudoephedrine. The British Society for Allergy and Clinical Immunology recommends loratadine at its lowest dose as a preferred choice if an antihistamine is required during breastfeeding.[1]

Effects on Lactation and Breastmilk

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[5][6] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[5] Whether lower oral doses of antihistamines own the same effect on serum prolactin or whether the effects on prolactin own any consequences on breastfeeding success own not been studied.

The prolactin level in a mom with established lactation may not affect her ability to breastfeed.

What can i take for allergies while breastfeeding

One mom out of 51 mothers who took loratadine while nursing reported that she had decreased milk production after taking loratadine 10 mg daily for less than one week at 4 months postpartum.[3]

References

1. Powell RJ, Du Toit GL, Siddique N et al.

What can i take for allergies while breastfeeding

BSACI guidelines for the management of chronic urticaria and angio-oedema. Clin Exp Allergy. 2007;37:631-50. PMID: 17456211

2. Hilbert J, Radwanski E, Affine MB et al.

What can i take for allergies while breastfeeding

Excretion of loratadine in human breast milk. J Clin Pharmacol. 1988;28:234-9. PMID: 2966185

3. Messinis IE, Souvatzoglou A, Fais N et al. Histamine H1 receptor participation in the control of prolactin secretion in postpartum. J Endocrinol Invest.

What can i take for allergies while breastfeeding

1985;8:143-6. PMID: 3928731

4.

What can i take for allergies while breastfeeding

Merlob P, Stahl B. Prospective follow-up of adverse reactions in breast-fed infants exposed to loratadine treatment (1999-2001). BELTIS Newsl. 2002;Number 10:43-51.

5. Merlob P.

What can i take for allergies while breastfeeding

Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal loratadine treatment (1999-2002). Unpublished manuscript.

What can i take for allergies while breastfeeding

6. Pontiroli AE, De Castro e Silva E, Mazzoleni F et al. The effect of histamine and H1 and H2 receptors on prolactin and luteinizing hormone release in humans: sex differences and the role of stress. J Clin Endocrinol Metab. 1981;52:924-8. PMID: 7228996


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